Building on the foundations of the nursing profession at the baccalaureate level, as articulated in the College of Nurses of Ontario (CNO) Competency Framework, theory and concepts will be critically appraised at the meso and macro levels. Multi-level factors that shape professional practice will be examined across diverse health care settings. Role competencies will be appraised: health equity, safety, and quality improvement. The influences of structural factors will be explored within the Canadian healthcare system.